Abstract
CORRIGENDACorrigendaPublished Online:01 Apr 1998https://doi.org/10.1152/jappl.1998.84.4.1/aOriginal articleMoreSectionsPDF (14 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Volume 83, August 1997 Page 522, Abstract: In line 20 of the Abstract, “arterial Po 2” was mistakenly printed instead of “arterial Pco 2.” The corrected Abstract is reprinted below. Waters, Karen A., André Laferrière, Julie Paquette, Cynthia Goodyer, and Immanuela R. Moss. Curtailed respiration by repeated vs. isolated hypoxia in maturing piglets is unrelated to NTS ME or SP levels. J. Appl. Physiol. 83(2): 522–529, 1997.—In early development, respiratory disorders can produce recurring hypoxic episodes during sleep. To examine possible effects of daily repeated vs. isolated hypoxic hypoxia, cardiorespiratory functions and central, respiratory-related neuromodulator levels in 21- to 32-day-old, chronically instrumented, unsedated piglets were compared between a fifth sequential daily hypoxia and an isolated hypoxia (10% O2-90% N2 for 30 min). Diaphragmatic electromyographic activity, heart rate and arterial pressure, and pH and gas tensions were measured. In vivo microdialysis, via chronically implanted guides, served to sample interstitial substance P (SP) and methionine-enkephalin (ME) at the level of the respiratory-related nucleus tractus solitarii (NTS). Compared with an isolated hypoxia, repeated hypoxia resulted in 1) lower respiratory frequency (f), ventilation equivalent, and arterial pH, higher arterial Pco 2 during hypoxia, and lower f in recovery from hypoxia; and 2) increased SP concentrations but no change in ME concentrations. We conclude that, in these maturing swine, repeated vs. isolated hypoxic exposure curtails respiratory responses to hypoxia by a mechanism(s) unrelated to SP or ME levels at the NTS.This article has no references to display. Download PDF Back to Top Next FiguresReferencesRelatedInformationRelated articlesCurtailed respiration by repeated vs. isolated hypoxia in maturing piglets is unrelated to NTS ME or SP levels 01 Aug 1997Journal of Applied Physiology More from this issue > Volume 84Issue 4April 1998Pages 1a-1a Copyright & PermissionsCopyright © 1998 the American Physiological Societyhttps://doi.org/10.1152/jappl.1998.84.4.1/aHistory Published online 1 April 1998 Published in print 1 April 1998 Metrics Downloaded 56 times
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