Abstract
An extensive study of four types of porous silica supports has been performed, with particular emphasis on their physical and morphological characteristics. These silicas were modified by reacting the surface silanol groups present with either 3-(trimethoxysilyl)propylmethacrylate or 3-glycidoxypropyltrimethoxysilane or 3-aminopropyltriethoxysilane, to produce derivatives with suitable functional groups for further utilisation in the immobilisation of biological compounds. The silicas and their derivatives used were fully characterised with regard to particle size distribution (laser light scattering), specific surface area (BET method), pore size distribution (gas adsorption and mercury porosimetry), density (helium pycnometry), yield of grafting (TGA) and chemical composition (FTIR/DRIFT).
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