Correlations between level of vitamin D serum and disease severity COVID-19

Abstract

Background: Corona virus disease (COVID-19) Was a respiratory disease. Severity of the disease was related to inflammation process. SCAP scoring system can be used to asses COVID-19 severity. Asses the severity of the disease is an important thing to determine the management. Vitamin D is shown to have anti-inflammatory effect. Vitamin D can downregulate cytokines storm and also induce innate immune activity. Here we want to know about the correlation between level of vitamin D and disease severity of COVID-19. Methods: Cross sectional study was observed 68 patient COVID-19 in Prof. Dr. I. G. N. G Ngoerah Denpasar hospital. They were asses with SCAP scoring system dan measured their vitamin D level at the same time. The correlation between two variable was analyze by Spearman correlation. Results: Among those 68 Sample, the median age of the sample is 64 years old, and 52.9 % of them are male. There is correlation between level of vitamin D and severity of COVID-19, the coefficient correlation was -0.47 with p<0.001. Conclusions: There is correlation between level of vitamin D and severity of COVID-19.