Abstract
The purpose of this study was to analyze the correlation of renal function indices with sub-foveal choroidal thickness (SFChT) in treatment-naïve (naïve) eyes with retinal vein occlusion (RVO) using swept-source optical coherence tomography (SS-OCT) and systemic workup. Retrospective chart review was performed from Dec 2016 to Sep 2019 in patients newly diagnosed with treatment-naïve unilateral RVO. Ocular parameters, including SFChT, and systemic profiles, including renal function indices, were reviewed. Simple and multiple linear regression analyses were performed to check if there was a correlation between renal profiles and SFChT. A total of 56 patients were included in the study; 34 of them were branch RVO and 22 were central RVO patients. Multiple linear regression analysis revealed that SFChT was positively correlated with estimated glomerular filtration rate (eGFR) (P < 0.001). SFChT showed significant correlation with renal function indices. In addition, choroidal thickness may be considered as systemic biomarkers for renal function.
Highlights
The purpose of this study was to analyze the correlation of renal function indices with sub-foveal choroidal thickness (SFChT) in treatment-naïve eyes with retinal vein occlusion (RVO) using swept-source optical coherence tomography (SS-Optical coherence tomography (OCT)) and systemic workup
Du et al reported that SFChT was significantly thinner in the RVO group than in the control g roup8
Tang et al reported that SFChT was significantly thicker in eyes with RVO than in fellow eyes9
Summary
The purpose of this study was to analyze the correlation of renal function indices with sub-foveal choroidal thickness (SFChT) in treatment-naïve (naïve) eyes with retinal vein occlusion (RVO) using swept-source optical coherence tomography (SS-OCT) and systemic workup. With recent technical developments, enhanced depth imaging OCT and swept-source OCT (SS-OCT) can visualize the deep choroid layer with accurate segmentation and high clarity. With recent technical developments, enhanced depth imaging OCT and swept-source OCT (SS-OCT) can visualize the deep choroid layer with accurate segmentation and high clarity8 Using these techniques, several studies have reported changes in sub-foveal choroidal thickness (SFChT) in eyes with RVO8,9. Balmforth et al reported that choroidal thickness is associated with renal function in patients with chronic kidney disease (CKD). We analyzed the correlation of renal parameters with SFChT in patients with RVO
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
