Abstract
Abstract: Coronary heart disease (CHD) is an unbalance condition between oxygen supply and demand in heart muscle which caused by coronary artery obstruction known as atherosclerosis. Both triglyceride and monocyte have important role in the process of atherosclerosis plaque forming which cause CHD. This research aimed to analyse correlation between triglyceride level and monocyte count in patients with coronary heart disease at Ulin General Hospital Banjarmasin on August 2014-August 2015. This research is an analytical observational research with cross-sectional approach. Total sample for this research are 94 CHD patients selected by inclusion criteria. The result discovered the average rate for triglyceride level is 114 mg/dL and for monocyte count is 0,62 thousand/µL. Based on result of data analysis with Pearson correlation test demonstrates the value of r=0,347 and p=0,01. It can be concluded that there is weak, significant and positive correlation between triglyceride level and monocyte count in CHD patients Keywords: triglyceride, monocyte, coronary heart disease
Highlights
Coronary heart disease (CHD) is a condition of unbalance between oxygen supply and demand in heart muscle resulting hypoxia and accumulation of metabolic waste in the heart muscle caused by narrowing of the coronary arteries due to the occurrence of atherosclerosis.[1]
The World Health Organization (WHO) on 2002 recorded that more than 11.7 million people died from CHD worldwide and is expected to increase by 11 million on 2020.2 Basic Health Research by the Ministry of Health on 2013 noted that the prevalence rate of CHD in Indonesia is 0.5% or about 883,447 Indonesians have CHD
According to data of Basic Health Research for South Kalimantan province recorded that the prevalence rate of CHD is 1,2 or 13,612 people of South Kalimantan population have CHD.[3]
Summary
Coronary heart disease (CHD) is a condition of unbalance between oxygen supply and demand in heart muscle resulting hypoxia and accumulation of metabolic waste in the heart muscle caused by narrowing of the coronary arteries due to the occurrence of atherosclerosis.[1]The World Health Organization (WHO) on 2002 recorded that more than 11.7 million people died from CHD worldwide and is expected to increase by 11 million on 2020.2 Basic Health Research by the Ministry of Health on 2013 noted that the prevalence rate of CHD in Indonesia is 0.5% or about 883,447 Indonesians have CHD. According to data of Basic Health Research for South Kalimantan province recorded that the prevalence rate of CHD is 1,2 or 13,612 people of South Kalimantan population have CHD.[3] From preliminary study at Ulin General Hospital Banjarmasin, it was obtained that 118 patients diagnosed CHD through coronary angiography method on August 2014August 2015.4. One of the risk factors of CHD is dyslipidemia, which is manifested by the increase of triglyceride levels.[5] Triglycerides are a type of fat that can be found in the blood.[6] Triglycerides are known not to be atherogenic, but according to Matsumoto et al, high triglyceride levels can promote the occurrence of atherosclerosis.[7] The condition of dyslipidemia increases the number of monocytes, an agranular leukocyte cell that plays a major role in the occurrence of atherosclerosis.[8]
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