Correlation study of deceleration capacity of heart rate, fibrillatory wave amplitude on lead V1 of surface electrocardiography, hsCRP and recurrence of atrial fibrillation after radiofrequency catheter ablation

Abstract

Objective To investigate the correlation between deceleration capacity of heart rate(DC), fibrillatory wave amplitude on lead V1 of surface electrocardiography, hsCRP and recurrence after radiofrequency ablation in patients with atrial fibrillation(AF). Methods Select the 70 AF patients who was operated with radio frequency catheter ablation for the first time from June 2015 to August 2016.According to the follow-up results, 45 cases were divided into the non-recurrence group and 25 cases in the recurrence group.General information, DC values, fibrillatory wave amplitude on lead V1 of surface electrocardiography, hsCRP of the two groups were collected and compared, establish Logistic regression model, screening of risk factors for AF patients after radiofrequency catheter ablation.DC values, fibrillatory wave amplitude on lead V1 of surface electrocardiography , hsCRP and the combination of the two, the combination of the three subjects were drawn the Receiver operating curve(ROC), to evaluate the predictive value of the combination of the three on the recurrence of the AF patients who was operated with radio frequency catheter ablation. Results The DC value(5.78±0.99)ms and hsCRP(1.85±0.77)mg/L in the recurrence group was higher than that in the non recurrence group(4.93±0.95)ms、(1.39±0.61)mg/L. The fibrillatory wave amplitude on lead V1 of surface electrocardiography in the recurrence group(0.095±0.013) mV was less than non recurrence group(0.110±0.017)mV(P<0.05). Multivariate Logistic regression analysis showed that the DC value(OR=3.99, 95%CI: 1.36-11.68, P=0.012), fibrillatory wave amplitude on lead V1 of surface electrocardiography(OR=0.000, 95%CI: 0.000-0.000, P=0.013), hsCRP(OR=5.15, 95%CI: 1.11-23.78, P=0.036)are independent risk factor for recurrence after radiofrequency ablation in patients with AF.The ROC curves of DC, fibrillatory wave amplitude on lead V1 of surface electrocardiography and hsCRP showed AUC were 0.731, 0.741 and 0.667. The ROC curves of combination of the three subjects showed AUC was 0.837, higher than their respective and the combination of the two values (P<0.05). Conclusion DC values, fibrillatory wave amplitude on lead V1 of surface electrocardiography and hsCRP had significant correlation with the recurrence of atrial fibrillation after adiofrequency catheter ablation. three combinations had predictive value in atrial AF patients who recurrent after radiofrequency catheter ablation. Key words: Deceleration capacity of rate; Fibrillatory wave amplitude; High-sensitivity C-reactive protein; Atrial fibrillation; Catheter radiofrequency ablation