Correlation study between DHFR enzyme and some biochemical parameters in diabetic type II patients

Abstract

Dihydrofolatereductase (DHFR)enzyme , Fasting Blood Sugar and some biochemical parameters were determined in (88) sample, (20) the control group which(10 males & 10 females) & (68) the patients(24 male &44 female) how were out-patient clinic in Baghdad hospital and had diabetic type II. There are significant differences in mean value between patient (male ,female) group and control group in FBG, urea, TG chol. HDL, creatinine, Na & K , while there is significant difference in mean value of ALP between patient group & control group and mean value of chloride between patient group & control group and there are highly significant differences in mean value between patient group and control group in ALT & AST. There was correlation between the DHFR and FBG,ALP, chl. TG in male patients and positive non significant between DHFR and ALT, AST. DHFR levels were negative significant correlated with urea HDL, Creat. Na but non- significant with K but the correlation was in female patients between the DHFR and FBG, ALP, Chl., TG, AST and positive non significant between DHFR and ALT. DHFR levels were negative significant correlated with Na but non- significant with urea,HDL,Creat. and K.