Correlation renal cortical echogenicity with serum creatinine in patients with chronic kidney disease

Abstract

Background: Sonography is the best screening modality to detect renal insufficiency in patients. Because ultrasonographic observations such as echogenicity, longitudinal length, parenchymal and cortical thickness reflect irreversible changes, when it comes to assessing the development of the disease, ultrasonography is a better imaging tool. Aims: Our aimed to compare renal echogenicity with serum creatinine levels and to investigate the importance of renal echogenicity in the detection of CKD development and the use of sonographic imaging in CKD classification. Materials and methods: 80patients above 30 years of age who had been diagnosed with CKD according to the guidelines of the National Kidney Foundation were included in the study. serum creatinine levels. Renal cortical echogenicity was compared with serum creatinine. A P value less than 0.05 was considered statistically significant. Results: In total 80 patients, 38 patients(48%) had sonological Grade 1 CKD, 29(36%) had Grade 2 CKD, 9(11%) had Grade 3 CKD, and 4(5%) had Grade 4 CKD. The mean serum creatinine was 2.7 mg/dl for Grade 1, 3.7 mg/dl for Grade 2 it is 3.9 mg/dl for Grade 3 and 7.8 mg/dl for Grade 4. There was a statistically significant positive association between serum creatinine and the grading of cortical echogenicity. The statistically significant positive association between mean longitudinal size and renal echogenicity, parenchymal thickness and renal echogenicity, cortical thickness and renal echogenicity was also statistically significant. Conclusion: In CKD patients, renal cortical echogenicity and its grading compared to longitudinal length, parenchymal thickness, and cortical thickness is the strongest sonographic parameter that correlates with serum creatinine. It can be used as a parameter of renal activity because renal cortical echogenicity has the advantage of being irreversible compared with serum creatinine levels.