Correlation of visualization of post embryo transfer air bubble with pregnancy rate

Abstract

We assessed 77 post-embryo transfer cases in surrogates aged 23 to 30 years in 6 months. Estradiol valerate 2 mg thrice daily was started from day 2 of the period in all subjects. Transvaginal scanning was done on day 8, and day 12 was done. Embryo transfer was planned when endometrial thickness was > 8 mm. Air bubble was visible in all subjects immediately after embryo transfer. Visualization of air bubbles was recorded one hour post embryo transfers after passing the urine. The pregnancy rate was assessed after 14 days in all subjects. There was no difference regarding demographic variables, number of embryos transferred, and embryo quality in all subjects. Cases were divided into 3 groups – Group A with clear visualization of the air bubble, Group B with a faint visualization of the air bubble, and Group C with an absent visualization of the air bubble. The pregnancy rate was 56.1% (32/57) in group 1, 78.6% in group 2 (11/14), and no pregnancies (0/6) in group 3. Visualizing an air bubble after one hour appears to predict the pregnancy rate. Negative visualization of air bubbles after one hour showed no pregnancies. Faint visualization indicated good pregnancy rates. But further, well-designed studies are required to predict the pregnancy rate more precisely.