Correlation of visual acuity and macular microstructural change after vitrectomy for idiopathic macular epiretinal membrane

Abstract

Objective To analyze the influence of macular structure change on visual acuity after vitrectomy for idiopathic macular epiretinal membrane(IMEM). Methods This is a retrospective case study.Total 49 eyes of 49 IMEM patients who underwent vitrectomy combined with macular epiretinal membrane peeling from Jan. 2016 and Dec. 2017 were collected.During 6 months follow-up, the preoperative and postoperative BCVA, central macular thickness(CMT), central photoreceptor thickness(CPRT), ellipsoid zone(EZ) integrity changes were observed.The correlations of postoperative BCVA, CMT, CPRT and integrity of ellipsoid zone were analyzed. Results Compared with preoperative BCVA, the postoperative BCVA were improved (F=8.114, P<0.05), the postoperative CMT, CPRT were significantly decreased, the difference were statistically significant (F=28.657, 10.530, P<0.05). The postoperative BCVA was positively related to the postoperative CMT, postoperative CPRT and preoperative BCVA (r=0.340, 0.742, 0.566, P<0.05). The postoperative BCVA was negatively related to the postoperative integrity of EZ (r=-0.628, P<0.05). Conclusion Vitrectomy for the treament of IMEM is effective, which can improve visual acuity, decrease macular edema.The postoperative visual acuity is related to the micostructural change of macular. Key words: Membrane, epiretinal, macular; Vitrectomy; Visual acuity; Tomography, optical coherence