Correlation of trinucleotide repeat with SARA score, age of onset and disease duration of genetically-positive spinocerebellar ataxia 2 Filipino family

Abstract

Background: Spinocerebellar ataxia 2 is a rare neurodegenerative disease characterized by a complex neurological presentation of ataxia of adult onset with an autosomal dominant inheritance caused by an abnormal expansion of trinucleotide CAG repeat.