Abstract
150 febrile patients included children (50), adult (50) and neonates (50) from outpatient departments and inpatients of private clinics and hospitals. Patients presented with fever and chills for more than 1 day to 3 days, throat infection, ear infection and cold and fever and only fever as the principal symptoms. After clinical examination all the patients were prescribed for Complete Blood Count (CBC) with differential count(DC) and C-reactive protein(CRP) tests, and in children below 14 years anti-Streptolysin O(ASO) tests ( 75) were prescribed.
 Patients treated with antibiotics previously two weeks before the study period were not included. Qualitative and quantitative tests were performed on all patients’ samples included in the study depending on the need/prescription by the physician or paediatrician. CBC, neutrophil count and CRP have been very useful indicators and significant in the diagnosis and treatment as well as follow-up of the febrile condition of the patients specially in patients suffering with bacterial infections. Even in patients with Dengue and malaria it gives a fair idea if there were leucocytosis or leukopenia, neutrophilia or neutropenia, thrombocytosis or thrombocytopenia.
 CBC: Complete blood count, DC: Differential count; MP: malarial parasite, CRP: C-reactive protein, ASO: Anti-Streptolysin O.
Highlights
Febrile illness indicates infection in active form
complete blood count (CBC), neutrophil count and CRP have been very useful indicators and significant in the diagnosis and treatment as well as follow-up of the febrile condition of the patients specially in patients suffering with bacterial infections
Even in patients with Dengue and malaria it gives a fair idea if there were leucocytosis or leukopenia, neutrophilia or neutropenia, thrombocytosis or thrombocytopenia
Summary
Febrile illness indicates infection in active form. Fever is a non-specific immune response exhibited by the host’s immune system whenever there is infection or inflammation. Clinical examinations with diagnostic investigations will give clear idea about the infection. If the infection is due to bacterial, viral, parasitic or fungal origin or in response to inflammation by the hosts immune system for different type of antigens. The complete blood count (CBC) is the most frequently requested blood test to understand the Haemoglobin percentage, total count, platelets cell counts and indices which give clear indication of infections and inflammation when levels are raised or decreased or within range. A major portion of the complete blood count is the measure of the concentration of white blood cells, red blood cells, and platelets in the blood. The primary points of interest in the CBC are often whether a patient is anaemic, whether the white blood cell count shows evidence of infection and whether the platelets are at a level that may affect haemostasis. Appropriate investigation can lead to specific diagnoses, and general and specific management measures can reduce both mortality and morbidity and permit genetic counselling and antenatal diagnosis in some cases[1]
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