Abstract
This study was conducted to compare the correlations between antioxidant activity and free radicals. Total Polyphenol and Flavonoid contents were the highest 31.97 ± 1.29 mg TAE/g and 96.1 ± 0.31 mg CE/g in hot water extract, respectively. FRAP activity was highest at 559.17 ± 2.69 mg TE/g in 60% EtOH extract. The RC50 values of DPPH and ABTS radical scavenging activity were lowest at 61.96 ± 5.01 μg/mL in 80% EtOH, 73.81 ± 0.16 μg/mL in 60% EtOH, respectively. The RC50 values of hydrogen peroxide scavenging activity and NO radical scavenging activity were lowest at 265.33 ± 3.88 μg/mL in 60% EtOH and 52.51 ± 8.54 μg/mL in hot water extract, respectively. The total polyphenol and flavonoid contents had significant correlation with the free radical scavenging ability and electron donating ability. On the other hand, there was confirmed significant correlation of free radical and antioxidant activities.
Highlights
Various external environmental factors such as environmental pollutants, ultraviolet rays, smoking, and alcohol intake in modern society are causing the occurrence of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS), which causes health problems
RNS refers to nitrogen compounds such as Nitric oxide (NO), NO2, and ONOO- can diffuse into the cell membrane and react with other free radicals
The yield of the plant extract is considered an important factor in the measurement of antioxidant activity, and even if the physiological activity of the extract is excellent, the economic efficiency is insufficient when the yield of the extract is low
Summary
Various external environmental factors such as environmental pollutants, ultraviolet rays, smoking, and alcohol intake in modern society are causing the occurrence of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS), which causes health problems. Active oxygen species such as superoxide anion radical, hydrogen peroxide, and hydroxyl radical etc. Are used in the process of oxygen oxidation during respiratory process and are produced through various metabolic processes. It is regulated by an in vivo antioxidant defense system such as SOD, glutathione, catalase and the like present in the human body (Hwang & Thi, 2014). Oxidative stress of the ROS and RNS can induce a variety of diseases that contribute to the aging process, and degenerative diseases, atherosclerosis, diabetes, hypertension, and cancer, etc. (Chung et al, 2000; Yu, 1996; Rittié & Fisher, 2002)
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