CORRELATION OF STRUCTURAL AND FUNCTIONAL FEATURES OF LEFT VENTRICLE WITH AMBULATORY BLOOD PRESSURE MONITORING DATA IN PATIENTS WITH ESSENTIAL HYPERTENSION

Abstract

Aim. To evaluate the relationship of 24-hour blood pressure (BP) monitoring data with myocardial mass and type of left ventricle hypertrophy (LVH) in non-treated patients with essential hypertension (HT). Patients and methods. We reviewed echocardiograms and BP monitoring data of 500 patients (250 females and 250 males; aged 53,1±12,2 y.o.). Results. Normal geometry of left ventricle (LV) was found in 143 patients (28,6%), concentric remodeling of LV – in 73 (14,6%), concentric LVH - in 138 (27,6%) and eccentric LVH – in 146 patients (29,2%). The least disturbances of 24-hour BP profile were observed in patients with normal LV geometry; 60,1% of patients had normal reduction of night BP. More than a third of patients had disturbances of circadian BP profile. Mostly severe disturbances of 24-hour BP profile were observed in patients with concentric and eccentric LVH. Circadian BP disturbances were revealed in two thirds of patients. Inadequate night BP reduction and inverted type of circadian BP profile predominated. Negative correlation between 24-hour systolic BP index and LV myocardial mass index was observed. Some LV structural disturbances as well as systolic dysfunction were revealed in patients with LV concentric remodeling. Besides HT of 3 grade and excessive night BP reduction were observed more often in these patients. Conclusion. The relationships between LV structural disturbances and 24-hour BP profile allow to reveal patients with unfavorable course of HT.