Correlation of some demographic parameters with clinical parameters of metabolic syndrome, bipolar affective disorders, and its therapeutics

Abstract

Background: Metabolic syndrome (MetS) has been found to be highly prevalent worldwide ranging from 11.2% to 47%. It is suggested that bipolar affective disorder (BPAD) and MetS share common risk factors including the treatment of the latter one, especially second-generation antipsychotics. The study tries to find out a significant correlation among various parameters, if any. Objectives: (i) To determine physical parameters such as blood pressure (BP) and waist circumference in drug-naive and drug-free patients vis-a-vis in control subject across various sociodemographic parameters; (2) to find out the prevalence of MetS in drug-naive/drug-free patients of bipolar disorder and control subjects and to compare with that of control subjects. Materials and Methods: The study was a comparative, cross-sectional, case-control, hospital-based study using purposive sampling method. Patients were taken up for the study from October 2013 to June 2015. The study included cases (79 = drug-naive 36 + drug-free 43; aged 16-55 years) and control (50). For control, people with General Health Questionnaire 12 score