Abstract
Introduction: Hypothyroidism is one of the most frequently encountered endocrine disorders in clinical practice; and its manifestations are highly variable. As thyroid hormones play an important role in normal functioning of virtually all tissues in the body, especially the cardiovascular system; its deciency can lead on to cardiac dysfunction causing electrocardiogram (ECG) changes. Aims: To study the pattern of ECG changes in hypothyroidism and to correlate with serum TSH values. Materials and methods: This cross-sectional observational study was done among 60 hypothyroid subjects at a tertiary care centre in Southern India. Thyroid Function Tests (TFT) and ECG were obtained and analysed using SPSS software v20. Results: Among 60 hypothyroid subjects, 54 (90%) were females and 6 (10%) were males. Twenty-eight subjects (46.66 %) had ECG changes with sinus bradycardia as the most common nding. Statistically signicant correlation was noted with pattern of ECG changes and serum TSH values; except for QTc prolongation. Conclusions: ECG changes were common among hypothyroid patients as compared to patients who were currently euthyroid. Early identication and treatment of hypothyroidism could prevent or revert the ECG changes; thus, reducing associated cardiovascular morbidity and mortality
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