Abstract
Correlation of serum PSA level with histomorphologic study in prostatic diseases - IJPO- Print ISSN No: - 2394-6784 Online ISSN No:- 2394-6792 Article DOI No:- 10.18231/2394-6792.2018.0117, Indian Journal of Pathology and Oncology-Indian J Pathol Oncol
Highlights
Worldwide, diseases of prostate gland are responsible for significant morbidity and mortality among adult males
Prostatic intraepithelial neoplasm and malignancy were common in 8th decade with mean
The age range of patients of benign prostatic hyperplasia and prostatic intraepithelial neoplasm is comparable to the study conducted by Wadgaonkar et al (2013).[9]
Summary
Diseases of prostate gland are responsible for significant morbidity and mortality among adult males. Aim: To evaluate the histomorphological spectrum of non-neoplastic and neoplastic lesions of prostate and to establish the correlation of histomorphological findings with serum prostate specific antigens levels. The PSA levels were estimated in biochemistry department using automated Chemiluminescence method on Beckman Coulter Access –II System. These values were correlated with histopathological diagnosis. Result: With 63.3%, benign prostatic hyperplasia was the most common lesion followed by Malignancy in 29.1% and prostatic intraepithelial neoplasia in 7.3% of total cases. Serum prostate specific antigens level was increased in 65.5% cases. Mean serum prostate specific antigens value of benign prostatic hyperplasia with and without inflammation is and10.9ng/ml and9.8ng/ml respectively. Mean serum prostate specific antigens value is 18.9 ng/ml in Low Grade and78.5 ng/ml in high grade prostatic intraepithelial neoplasm.
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