Correlation of Preterm Infant Salivary Cortisol Levels with Scores on the Neonatal Infant Stressor Scale

Shaliz Pourkaviani,Annemarie Stroustrup-Smith,Xueying Zhang,Madiline D’Agostino,Rebecca Satty,Emily Spear

doi:10.29024/jsim.15

Abstract

Correlation of Preterm Infant Salivary Cortisol Levels with Scores on the Neonatal Infant Stressor Scale

Highlights

In this study, we compared acute and chronic Neonatal Infant Stressor Scale (NISS) scores to an accepted biomarker of infant stress response, salivary cortisol, in a cohort premature infants born 28-0/7–32-6/7 weeks gestation through the course of the neonatal intensive care unit (NICU) hospitalization
The scale consists of 35 acute items and 19 chronic items that are thought to capture stressful events that were chosen by NICU caregiver estimation of stressful events during the NICU hospitalization and
Using a Pearson correlation analysis and mixed-effects model we concluded that both acute and chronic NISS scores were significantly correlated with salivary cortisol (P-values < 0.001)

Summary

Introduction

We compared acute and chronic NISS scores to an accepted biomarker of infant stress response, salivary cortisol, in a cohort premature infants born 28-0/7–32-6/7 weeks gestation through the course of the NICU hospitalization. Shaliz Pourkaviani1, Xueying Zhang2, Emily Spear2, Rebecca Satty2, Madiline D’Agostino2 and Annemarie Stroustrup2 1 Mount Sinai Hospital, US 2 Icahn School of Medicine at Mount Sinai, US Corresponding author: Shaliz Pourkaviani (shaliz.pourkaviani@mountsinai.org)

Results

Conclusion