Correlation of Patient Features of Covid-19, Laboratory Tests and Computed Tomography Findings: Single-Center Retrospective Study

Abstract

Aim: Computed Tomography (CT) findings, clinical and laboratory data are very important in the diagnosis and treatment process of Coronavirus Disease 2019 (COVID-19). In this study, the relationship between these findings was investigated. Material and method: 93 patients with positive Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) test for SARS-CoV-2 were included in the study. CT findings, laboratory tests, and the World Health Organization Clinical Progress Scale (WHO-CPS) were evaluated. Results: Of the patients, 52 were male and 41 were female. The mean age was 46. The most common laboratory finding is high CRP levels (67.74%). GGO, consolidation, halo sign and air bronchogram were most frequent CT findings. The mean of CT score was 4.91. A statistically significant positive correlation was found between CT score and age, D-dimer, CRP, ferritin and fibrinogen. There was a significant negative correlation between CT score, lymphocyte count and oxygen saturation. There was no correlation between CT score and procalcitonin, gender and presence of comorbid disease. There was a moderate negative correlation between CT score and IL-6 blocker use and corticosteroid therapy, and a mild negative correlation between CT score and favipravir use. The correlation between CT score and immunosuppressant use was not significant. We also found a moderate positive correlation between WHO-CPS and CT scores. Conclusion: The CT score is correlated with some laboratory and clinical markers, and we think that these findings indicate that CT is a very useful test in the diagnosis as well as in the follow-up.