Correlation Of Parameters Of Semen Analysis In Oligospermia In Infertility

Abstract

Background: Various semen parameters including morphology, vitality, motility, maturation, pH, count, agglutination and biochemical parameters altogether determine the overall quality of semen. Common factors associated with oligospermia are diseases (genetic, infectious, hormonal and obstructive), smoking, environmental factors such as radiation, heavy metal poisoning, overheating of testicles. Objective: Semen analysis in infertile males of various age group with possible correlation of parameters in relation to oligospermia. Materials and methods: This cross-sectional descriptive observational study included 150 semen sample received from various infertility clinics, obstetric gynaecology clinics, In vitro fertilization centers, and from individuals with infertility problems. The study was conducted from July2021-February2022. Parameters studied included volume, liquefaction time, pH, count, motility, morphology, immature forms, agglutination, leucocytes, and fructose. Results: Out of 150 cases, majority belonged to the age group of 31-40years, mean age was 33.14 years. Seventy-three cases (48.7%) were normal, six (4%) showed azoospermia, 71 (47.3%) showed oligospermia. Parameters correlated positively with oligospermia are age (0.008 Pearson correlation, 0.946 p value, not significant), pH (0.194 Pearson correlation, 0.106 p value, not significant), liquefaction time (0.106 Pearson correlation, 0.378 p value, not significant). Parameters correlated negatively with oligospermia are volume (-0.58 Pearson correlation, 0.633 p value, not significant) and motility (-2.77 Pearson correlation, 0.19 p value, significant) Conclusion: The study showed a positive correlation of oligospermia with age, pH, liquefaction time and negative correlation with volume and motility. The study also showed a significant association between oligospermia and motility, morphology, agglutination and fructose.