Correlation of pain and depression with tumor extent in patients with resected pancreas cancer.

Abstract

e14616 Background: Psychological tools have been used to assess pain and depression in various cancers and their impact on patient quality of life (Qol). Little is known about such factors in pancreas cancer, especially the correlations of QoL with pathologically-proven disease tumor extent. Methods: We prospectively examined QoL using Fact-Hep and CES-D scores in patients with resected pancreas cancer and correlated scores at presentation with baseline tumor extent. Results: 113 patients were evaluated. There were 63% males and 37% females. Pain was a presenting symptom in 38% in each gender and jaundice was the presenting symptom in 10% of females and 14% of males. Patients with Pain or No Pain at presentation were compared. Patients with pain had more metastases than patients without pain (52% vs. 27%). An ANOVA found higher CEA and depression scores (CES-D) and lower Physical and Functional well-being (FACT-HEP) for patients with pain than those without pain. No differences were found between groups f...