Abstract

Bioactive glass (BG) is considered to be one of the most remarkable materials in the field of bone tissue regeneration due to its superior bioactivity. In this study, both un-treated and polyethylene glycols (PEG)-treated BG particles were prepared using a spray pyrolysis process to study the correlation between particle morphology and degradation behavior. The phase compositions, surface morphologies, inner structures, and specific surface areas of all BG specimens were examined by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and nitrogen adsorption/desorption, respectively. Simulated body fluid (SBF) immersion evaluated the assessments of bioactivity and degradation behavior. The results demonstrate three particle morphologies of solid, porous, and hollow factors. The correlation between porosity, bioactivity, and degradation behavior was discussed.

Highlights

  • The superior bioactivity of bioactive glass (BG) has been demonstrated to bond with living tissues and to stimulate new tissue growth due to their similar compositions in the Main inorganic components of human bones [1,2]

  • For the un-treated powder, the X-ray diffraction (XRD) pattern shows the absence of any crystalline peak except for a broad band between the diffraction angles of 20◦ and 40◦

  • For the 0.1 M, 0.3 M, and 0.5 M polyethylene glycols (PEG)-treated powders, the similar XRD patterns have been detected, which supports that the PEG-treated powders are amorphous

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Summary

Introduction

The superior bioactivity of bioactive glass (BG) has been demonstrated to bond with living tissues and to stimulate new tissue growth due to their similar compositions in the Main inorganic components of human bones [1,2]. Properties such as biocompatibility and degradability have received numerous attention in the fields of tooth fillers, drug carriers, and bone implants in recent years [3,4,5].

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