Abstract
Objectives: To document the leptin level and its effect on obese and non-obese. Study Design: Observational comparative study. Setting: CMH Institute of Medical Sciences Bahawalpur, Sharif Medical and Dental College and Sharif College of Nursing Lahore. Period: From 1st January 2018 to 1st January 2019. Material & Methods: Ninety healthy obese and non-obese subjects who were selected by non-probability consecutive sampling technique included in study. Ethical approval was obtained before start of study. SPSS version 23 was used for data analysis; main variables of study were age, BMI and leptin resistance. P value ≤0.05 was considered as significant. Results: The mean leptin level in obese and non-obese was 53.75±7.54 and 50.62±7.18, respectively. There difference was statistically significant among the groups, (p=0.000). Conclusion: Results of our study reveal that leptin level is a related factor in the pathogenesis of obesity.
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