Abstract
Background: Chronic lead exposure from the lead-acid–battery manufacturing process has been linked to a variety of health effects, including dental health, cardiovascular disease risk, Matrix–gamma– carboxy glutamic acid protein (MGP) polymorphism, oxidative stress, immunological, genotoxicity, reproductive, neuropsychological, and pteridine metabolism with neurotransmitters synthesized.
 Aim of the Work: effects of lead exposure on calcium metabolism in battery workers.
 Subjects and Methods: The present study will be conducted in Department of Biochemistry, Index Medical College and research center, Indore. A total of 100 lead exposed battery workers and 100 aged (20-60 yr) matched non lead exposed controls. Blood sample was withdrawn from the anticubital vein and centrifuged to obtain serum after that serum was quantitatively analyzed for lead level, calcium, phosphorous and vitamin D3. 
 Result and Conclusion: In lead-exposed battery workers, correlation analysis revealed a strong negative connection between blood lead levels and serum vitamin D levels. Similarly, serum calcium levels were found to be inversely linked with blood lead levels.
 Keywords: Battery workers, Lead
Highlights
Lead poisoning has been the most widespread environmental health concern confronting humanity in recent years
Blood sample was withdrawn from the anticubital vein and centrifuged to obtain serum after that serum was quantitatively analyzed for lead level, calcium, phosphorous and vitamin D3
Serum calcium levels were found to be inversely linked with blood lead levels
Summary
Lead poisoning has been the most widespread environmental health concern confronting humanity in recent years. Despite being a naturally occurring component of the earth's crust, lead does not become dangerous until it is extracted and turned into human-made items. When it comes into contact with humans, it is swiftly absorbed in blood and soft tissues and slowly absorbed in bones[1]. Lead is prevalent in locations where lead pipes are utilized for potable water supply, in addition to petroleum-related emissions. Absorption of old leaded paint and glazes used in ceramics is linked to lead exposure in the home. Many previous studies have found that more than half of India's children have high blood lead levels (te g/dL)[2]
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