Abstract
COVID-19 is an acute infectious respiratory disease caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus. Changes in inflammatory mediators in the laboratory can be related to the phase of the disease course and the patient's clinical course. The results help determine the degree and predict the severity of COVID-19. This study aims to determine the correlation between Interleukin 6 levels and quantitative CRP levels to the severity of COVID-19 disease. This study is an analytic observational study with a cross-sectional design. This research was conducted in the COVID-19 isolation ward of RSMH Palembang from September 2021 to February 2022, with the subjects confirmed COVID-19 with various severity. Those confirmed with COVID-19 were interviewed, checked vital signs, laboratory tests for Interleukin 6, and quantitative CRP. Statistical analysis of the correlation test used Spearman and Gamma. Sample of 39 patients, consisting of 16 patients (41%) moderate, 15 patients (38.5%) severe, 8 patients (20.5%) critical. There was a significant correlation between interleukin six levels and the degree of COVID- a disease with r = 0.719. A positive correlation with moderate strength was found between interleukin six levels and quantitative CRP levels so that these two parameters can be used as predictors of the severity of COVID-19 and have a positive correlation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
