Correlation of glycated haemoglobin with fasting and post prandial blood glucose in Type 2 diabetes

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Diabetes mellitus is a group of metabolic disorders characterized by high blood sugar levels and this chronic hyperglycemia is responsible for most of the complications of the disease. Glycated haemoglobin or HbA1C is a marker of this hyperglycemia and its complications. The aim of this study is to find out the correlation between HbA1C and FBS, PPBS and hence its effectiveness in assessing the glycemic contol in type 2 diabetic patients.In this cross sectional study, FBS, PPBS and HbA1C values were recorded in the study population which includes 605 type 2 diabetic patients visiting the hospital. FBS and PPBS were estimated using GOD- POD method. HbA1C was analyzed using particle enhanced immunoturbidimetric method and the data analysed and correlated with FBS and PPBS. There was a significant correlation between FBS, PPBS and HbA1C in the study population. It has also been found that PPBS shows a marginally better correlation(0.79) with HbA1C than FBS(0.77). This emphasizes the role of HbA1C as an indicator of blood glucose control, as it correlates well with FBS and PPBS. Maintenance of strict glycemic control retards the development of complications of diabetes, which improves the quality of life of a diabetic patient. This glycemic control can be assessed with reasonable accuracy using HbA1C, as it has been found to correlate well with FBS and PPBS levels, more so with the PPBS levels.