Correlation of Disc Damage Likelihood Scale, Visual Field, and Heidelberg Retina Tomograph II in Patients with Glaucoma

Abstract

To correlate the analysis of the optic nerve head (ONH) obtained with Disc Damage Likelihood Scale (DDLS), Heidelberg Retina Tomograph II (HRT II), and visual field (VF) parameters (Aulhorn scale, mean deviation [MD], and pattern standard deviation [PSD]) in patients with glaucoma. Sixty-five eyes were evaluated using the DDLS classification. Fifty-seven eyes had stable primary open-angle glaucoma (POAG) and eight eyes were normal (control group). Classification of the ONH was performed using the HRT II, with Moorfields Regression Analysis (MRA) and Cup Shape Measure (CSM) indexes. The VF was examined by Full Threshold test (30-2) using the Humphrey Field Analyzer (HFA) perimeter and evaluated by three Aulhorn's scale of 0 to 6, and two global indices, MD and PSD. The amount of ONH damage as estimated by the DDLS correlated well with topographic damage determined by HRT II (r=0.923 with MRA and r=0.807 with CSM) and with visual field loss as measured by the MD (r=-0.792) and PSD (r=0.718) of the HFA and Aulhorn field staging system (r=0.849). This study shows that evaluation of the ONH using the DDLS provides information that correlates well with VF and with data obtained from HRT II.