Correlation of depression, anxiety and stress level on dry eye disease severity

Abstract

Dry eye disease (DED) is a multifactorial disease of the tears and ocular surface. Dry eye disease is an important public health problem which lead to ocular discomfort and disrupt on the patient’s daily activity. The prevalence of DED varies with age and demographic between 5,5% - 50,1% and increased with age and has been associated with chronic illness such as diabetes melitus and hypertension. This study to investigate the correlation between DED with depression, anxiety and stress. Research location at Sanglah Hospital eye policlinic in Denpasar-Bali with 93 sample were analyzed. Data was analyzed to get correlation between DED and depression, anxiety and stress with sex, education, work, and chronic illness used SPSS program. Ninety-three patients admitted to eye policlinic, mostly female 50 (53,8%) with median age 45,00 ±12,445. The correlation between DED and depression, anxiety and stress showed inversely correlation. The correlation between OSDI score with depression, anxiety and stress showed positive correlation (depression r 0,27, p=0,008; anxiety r 0,31, p= 0,003; stress r 0,29, p=0,004). There are correlation of OSDI score with depression, anxiety and stress but not correlated with objective DED tests. Higher OSDI score was correlated with higher depression, anxiety and stress score.