Abstract
Correlation Of Cryptococcal Antigen Assay With C-reactive Protein As Serum And Urine Biomarker In Cryptococcal Meningitis: Experience In A Tertiary Hospital
Highlights
Cryptococcosis, caused by Cryptococcus spp., is one of the most common opportunistic infections among human immunodeficiency virus (HIV) infected individuals.[1]
Given the high incidence, morbidity and mortality associated with cryptococcal meningitis, it would be ideal if a screening test could be used to exclude this diagnosis based on the presence of biomarkers in serum or urine which would mean less discomfort for the patient in addition to decreased laboratory examination costs
Out of 1080 cerebrospinal fluid (CSF) samples from suspected cases of meningitis that were received during January 2010 to 2011 in the Microbiology Laboratory, 54 samples were from patients strongly suspected of fungal meningitis
Summary
Cryptococcosis, caused by Cryptococcus spp., is one of the most common opportunistic infections among human immunodeficiency virus (HIV) infected individuals.[1]. An estimated 88% of global cases and more than 90% of deaths from cryptococcal meningitis occur in sub-Saharan Africa and Southeast Asia.[5]
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