Abstract

OBJECTIVES This study correlated the multi - detector computed tomography (MDCT) calcium scores with the results of coronary angiography in diabatic and/or hypertensive patients with atypical angina pectoris in order to assess its value to predict or exclude significant coronary artery disease (CAD). BACKGROUND Muti-detector computed tomography is a sensitive method to detect coronary calcium. However, it is unclear whether it may play a role as a filter before invasive procedures in patients with atypical angina pectoris. METHODS A total of 150 patients (116 men and 34 women) with diabetic and/or hypertension for at least 5 years and atypical angina pectoris from a single center were included in our study. patients underwent calcium screening with MDCT and have calcium score more than 100 , then all patient underwent invasive coronary angiography. RESULTS The Mean age was 62±5.7 and 77.3% were male, 78% of men and 88.2 % of women revealed significant coronary stenoses (> 50% lumen narrowing of left main trunk stenosis and > 70% stenosis of any epicardial coronary artery). Significant correlation between calcium scoring and significant coronary artery stenosis was seen (P: 0001). A 70% were DM, 90% were hypertensive and 61.3% were HTN and DM. The LAD artery was the most stenotic artery by 53.3% followed by RCA (37.3%) and finally LCX (30.7%). one significant coronary artery was 42% followed by two significant CAD (26.7%), while 9.3% included three-vessel disease. The significant coronary artery diseases was increased with age ( P: 0003). CONCLUSIONS Coronary calcium proved to have good diagnostic performance for significant coronary artery stenosis in patient with atypical angina pectoris.

Highlights

  • IntroductionIntroduction first pointCoronary angiography is over-used and low-yield. And second point: Coronary heart disease is the leading cause of mortality in the Palestine and worldwide

  • Introduction first pointCoronary angiography is over-used and low-yield

  • This study describes the value of multi - detector computed tomography (MDCT) calcium screening in patients with atypical angina pectoris with diabetes and/or hypertension for at least 5 years who were referred to our center with suspected coronary artery disease (CAD) to be proven or excluded by coronary angiography

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Summary

Introduction

Introduction first pointCoronary angiography is over-used and low-yield. And second point: Coronary heart disease is the leading cause of mortality in the Palestine and worldwide. The current gold standard to evaluate coronary artery disease is invasive coronary angiography (ICA). Coronary intervention procedures rose by 48 % over the last 4 years from Studies have shown that the coronary artery calcium score (CACS) is usef a rate of 80 per 100,000 population in 2015 to 155 per 100,000 population refined risk stratification, with high-risk patients and those with dia in 2018. The significant coronary artery stenosis among patients underwent Our aim of this study to confirm correlation between computed tomographic ca diagnostic coronary angiography were 54.3% of patients with stable score with intermediate or high risk (Agatston score >100) and invasive cor ischemic heart disease, 66.7% in patients with unstable angina pectoris angiography (ICA) in patient with age more than 40 years and have diabetes a and 92.7% in patient with ST elevation myocardial infarction. All patient with previous documented CAD by invasive coronary angiography, all patient with previous Coronary artery by-pass grafting

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