Abstract

The validity of bedside clinical tests of cognition has been questioned, particularly in patients with affective symptoms. Using clinical tests of cognition and a full neuropsychological bauery, we studied 35 consecutive patients with untreated Cushing's syndrome, which is characterized by depressed mood and cognitive abnormalities. The results for serial sevens and recall of three cities after five minutes correlated significantly with a number of verbal and nonverbal subtests of the neuropsychological bauery. We conclude that in patients with both affective and cognitive disturbances these bedside clinical tests are a good measure of the degree of neuropsychological deficit.

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