Correlation of aneurysm height/size ratio of blood vessel diameter and the risks of aneurysm rupture

Abstract

Objective To investigate the relationship between the maximum height of anterior communicating artery(AComA)aneurysm or the size ratio(SR)of mean diameter of peripheral blood vessels and aneurysm rupture. Methods The morphological parameters of the aneurysms in 594 patients with AComA aneurysm admitted to the Department of Neurosurgery, the First Affiliated Hospital of Wenzhou Medical University from October 2010 to December 2014 were analyzed retrospectively. There were 529 patients with ruptured AcoA aneurysms and 65 with unruptured AComA aneurysms. The maximum height of aneurysms and the mean diameter of the peripheral vessels were collected respectively, and the relationship between SR and AComA aneurysm rupture in both of them were analyzed at the same time. Results Among the 594 patients with AComA aneurysm, the mean value of the maximum height of the aneurysms in the ruptured aneurysms was 4.26±2.19 mm. It was obviously larger than 2.82±2.04 mm of the unruptured aneurysms, and the mean diameter of the peripheral blood vessels of the ruptured aneurysms was 1.91±0.54 mm, it was smaller than the mean diameter of 2.16±0.49 mm in the peripheral blood vessels of the unruptured aneurysms. There was significant difference between both of them(all P 2 group was significantly higher than that in the SR ≤2 group(P<0.001). After the analysis of ROC curve, the area under the curve of the SR ≤2 value of AComA aneurysms was 0.744, and the optimal cut-off value was 1.19. Conclusions The size of SR value is significantly associated with the rupture of AComA aneurysms. When determining the treatment options for patients with AComA aneurysm in clinical practice, the SR value can be considered as a reference factor. Key words: Intracranial aneurysm; Anterior communicating artery; Rupture risk; Morphology