Abstract
Purpose:To evaluate the correlation between visual field index (VFI) and both structural and functional measures of the optic disc in primary open angle glaucoma patients and suspects.Methods:In this retrospective study, 162 glaucoma patients and suspects underwent standard automated perimetry (SAP), retinography, and retinal nerve fiber layer (RNFL) measurement. The optic disc was stratified according to the vertical cup/disc ratio (C/D) and sorted by the disc damage likelihood scale (DDLS). RNFL was measured with the optical coherence tomography. The VFI perimetry was correlated with the mean deviation (MD) and pattern standard deviation (PSD) obtained by SAP, and structural parameters by Pearson's correlation coefficients.Results:VFI displayed strong correlation with MD (R = 0.959) and PSD (R = −0.744). The linear correlations between VFI and structural measures including C/D (R = −0.179, P = 0.012), DDLS (R = −0.214, P = 0.006), and RNFL (R = 0.416, P < 0.001) were weak but statistically significant.Conclusion:VFI showed a strong correlation with MD and PSD but demonstrated a weak correlation with structural measures. It can possibly be used as a marker for functional impairment severity in patients with glaucoma.
Highlights
The results of this study revealed that visual field index (VFI) displayed a strong positive correlation with mean deviation (MD) and a weak negative correlation with pattern standard deviation (PSD)
The correlation between VFI and both MD and PSD was linear. This correlation was expected since VFI, MD and PSD are all parameters assessed by the same equipment (Humphrey Field Analyzer) using decibels
The strong positive correlation found in the study (R = 0.956) means that the worse the MD, the lower the VFI value
Summary
The mean deviation from standard automated perimetry is generally used to evaluate glaucoma progression. Since it can be affected by media opacity, a new functional index has been developed. The visual field index (VFI) is a new global metric that represents the entire visual field as a single number. It is estimated by calculating age corrected defect depth at the test points
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
