Correlation between ultrasound parameters and hormone level in patients with polycystic ovary and polycystic ovary syndrome

Abstract

A total of 104 patients with polycystic ovarian changes on ultrasound were divided into polycystic ovary syndrome (PCOS) and polycystic ovaries (PCO) groups according to their clinical symptoms and endocrine examinations. And 40 women with normal ovulation served as the controls. Ovarian volume (OV), ovarian stroma area (SA), ovarian total area (TA) and SA/TA ratio were measured by transvaginal ultrasonography. Their endocrine hormone levels were determined. Patients with PCOS showed significantly higher OV, SA, TA and SA/TA than those of PCO and control groups. SA/TA was positively correlated with testosterone. The median serum levels of anti-Mullerian hormone (AMH) and inhibit B in the PCO group were intermediate between those in control and PCOS groups. AMH and inhibin B of PCOS were higher than the PCO and control groups. It indicated that the levels of AMH and inhibit B were associated with the degree of polycystic ovaries and they could be used to differentiate PCOS and PCO. SA/TA is associated with the elevated serum testosterone of PCO. And SA/TA is an important ultrasonic parameter for diagnosing PCOS. Key words: Polycystic ovary syndrome; Ultrasonograph, Doppler, color