Abstract

Background and Aim: Diabetes has emerged as an important global health concern because of itsvarious adverse effects on the ocular tissue. The present study was done to study the correlationbetween type 2 diabetes mellitus and central corneal thickness in patients coming to the tertiarycare institute of Gujarat, India. Material and Methods: The present study was conducted over 1year at the tertiary care institute of Gujarat, India.50 patients with type 2 diabetes mellituspreviously diagnosed by a physician on treatment and 50 age-matched controls who are non-diabetics on history and blood sugar levels were enrolled. The central corneal thickness wasmeasured using an ultrasound pachymeter using multiple reading single point modes by a singleperson. Results: The mean central corneal thickness in diabetics was 565 ± 21 micrometres and innon-diabetics was 517 ± 20 micrometres. The central corneal thickness was found to be higher inpatients with type 2 diabetes mellitus when compared to non-diabetics. Conclusion: Patients withtype 2 diabetes mellitus were found to have thicker corneas as compared to non-diabetics. Thisshould take into consideration while interpreting intraocular pressure and before any refractivesurgeries in diabetics.

Highlights

  • Diabetes mellitus is a syndrome characterized by inappropriate hyperglycemia and is chronically associated with microvascular and macrovascular complications

  • The central corneal thickness was found to be higher in patients with type 2 diabetes mellitus when compared to non-diabetics

  • Patients with type 2 diabetes mellitus were found to have thicker corneas as compared to non-diabetics. This should take into consideration while interpreting intraocular pressure and before any refractive surgeries in diabetics

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Summary

Introduction

Diabetes mellitus is a syndrome characterized by inappropriate hyperglycemia and is chronically associated with microvascular and macrovascular complications. The main indicators of diabetes in ocular tissues are retinopathy, cataract and glaucoma The corneal changes associated with Diabetes mellitus is known as diabetic keratopathy, a lesser-studied pathology [3]. It can have varied presentations like decreased corneal sensitivity, epithelial disorders like superficial punctate keratitis and epithelial erosions, thickened basement membrane [4,5]. The present study was done to study the correlation between type 2 diabetes mellitus and central corneal thickness in patients coming to the tertiary care institute of Gujarat, India. The central corneal thickness was found to be higher in patients with type 2 diabetes mellitus when compared to non-diabetics. This should take into consideration while interpreting intraocular pressure and before any refractive surgeries in diabetics

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