Abstract
PurposeThe aim of this study was to assess the relationship between size of thyroid nodules at computed tomography (CT), magnetic resonance imaging (MRI) or positron emission tomography CT (PET-CT), and size at ultrasound. Materials and methodsWe performed a retrospective review of thyroid ultrasound studies over a 2-year period. ResultsA total of 307 patients were included in the study. There was a statistically significant difference between the size of nodules measured on ultrasound compared with cross-sectional imaging (P < .001). American College of Radiology white paper recommendations would have decreased ultrasound referrals by 24% without any additional missed malignancies. ConclusionCross-sectional imaging underestimates the size of thyroid nodules; however, the difference is small and likely not clinically significant.
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