Abstract
Assessment of glomerular filtration rate (GFR) in heart transplant (HTx) patients is based on serum creatinine (sCr), the endogenous creatinine clearance (C Cr) and radionuclide GFR (rGFR); however, the latter is expensive and time consuming. We reviewed the data of 32 adult HTx patients to determine the correlation between sCr, C Cr, the calculated C Cr (Calc.C Cr; based on gender, age, weight and sCr) and rGFR in long-term (>1 year) HTx patients receiving calcineurin inhibitors. The Calc.C Cr was found to have the best correlation with rGFR ( r 2 = 0.65), followed by C Cr ( r 2 = 0.53) and sCr ( r 2 = 0.38). The use of Calc.C Cr to estimate GFR may be cost-effective in assessing renal function after HTx.
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