Correlation between Serum Cholesterol and Serum Albumin Level in Childhood Nephrotic Syndrome

Abstract

1.1.Hypercholesterolemia, a common secondary laboratory abnormality, is very prevalent in children with nephrotic syndrome. 1.2.Objective: The aim of this study was to evaluate the direct relationship between serum cholesterol and serum albumin in childhood nephrotic syndrome. 1.3.Patients and method:This cross sectional comparative study was performed on 60 children with the age of 2 years to 8 years with nephrotic syndrome in Department of Pediatric Nephrology, Comilla Medical College Hospital from January 2013 to December 2013. Serum albumin and serum cholesterol was measured by enzymatic colorimetric method. The relationship between serum cholesterol and serum albumin was measured by Pearson’s correlation. 1.4.Results: The mean cholesterol level in cases was 240(±07) mg/dl. And mean serum albumin level of cases was (1.88±.37)mg/dl. Pearson’s correlation test between serum cholesterol and serum albumin level of cases were significant (p=<0.05). 1.5.Conclusion: These results suggest that in the childhood nephrotic syndrome, there is a negative correlation between serum cholesterol level and serum albumin level.