Correlation Between Serum Calcium, Phosphorus, and Alkaline Phosphatase Indices With Lumbar Bone Mineral Density In Active And Inactive Postmenopausal Women

Abstract

Background and Aim Menopause is a period in a woman’s life that can be physically damaging. However, its effect on bone mineral density is still debatable. This study investigated the relationship between serum calcium, phosphorus, and alkaline phosphatase indices with lumbar bone mineral density in active and inactive postmenopausal women. Methods & Materials The number of subjects was 55 active postmenopausal women and 60 inactive postmenopausal women aged 45 to 85 years. Serum indices of calcium, phosphorus, and alkaline phosphatase and anthropometric of the subjects were measured. The Pearson correlation coefficient test was used to analyze the research data. SPSS software v. 26 was used to analyze the data. Ethical Considerations This study was approved by the Research Ethics Committee of Allameh Tabataba’i University with code IR.ATU.REC.1399.038. Results The results showed a significant correlation between serum levels of alkaline phosphatase (P=0.021), calcium (P=0.019), and phosphorus (P=0.011) with lumbar bone mineral density in active postmenopausal women and also between body mass index with lumbar bone mineral density in both groups of active (P=0.014) and inactive (P=0.038) postmenopausal women. No significant relationship was found between other indicators. Conclusion According to the results of the present study, being active may have had beneficial effects on bone metabolism and has led to a better state of bone mineral density. It may also help to use these blood and anthropometric variables in identifying people at risk for osteoporosis in adulthood and old age.