Abstract
Background: Tuberculosis (TB) is contagious and airborne. TB was one of the top 10 causes of death worldwide in 2017. It is also the leading killer of people with HIV and a major cause of deaths related to antimicrobial resistance.
 Methods: Microscopically confirmed TB patients were included in the cases group and healthy individuals in the control group. Serum Ca was estimated by kit method, by auto analyzer. ANOVA and t- test was used to find the statistical significance.
 Results: The mean serum Ca was 7.32±1.22 mg/dl in TB and 9.41±2.13 mg/dl in controls. The mean serum Ca levels were 7.22±1.20 mg/dl, 7.14±1.14 mg/dl, 7.12±1.10 mg/dl and 7.06±1.02 mg/dl respectively for scanty, 1+. 2+ and 3+; statistically the difference were not significant (P > 0.05) between the grades.
 Conclusion: Hypocalcemia observed in pulmonary tuberculosis patients. No correlation was found between the mean serum Ca levels and grading.
 Keywords: Calcium, TB, AFB.
Highlights
Mycobacterium tuberculosis (MTB) complex, an acid fast bacillus (AFB) is the causative agent of tuberculosis (TB).[1]
Hypocalcemia observed in pulmonary tuberculosis patients
No correlation was found between the mean serum Ca levels and grading
Summary
Mycobacterium tuberculosis (MTB) complex, an acid fast bacillus (AFB) is the causative agent of tuberculosis (TB).[1]. TB was one of the top 10 causes of death worldwide in 2017. 2 It is the leading killer of people with HIV and a major cause of deaths related to antimicrobial resistance. If the intake of nutrients is hampered, leads to deficiency and the individual prone for infections. In this regard, minerals play an important role. Several investigators studied on level of serum Ca among the TB patients. We cannot find studies on correlation between levels of serum Ca and smear grading. A study was undertaken to find the serum Ca levels and its correlation with smear grading among the PT individuals
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