Correlation between quality of life and joint health status of adult hemophilia patients

Abstract

Objective To investigate the correlation between the quality of life and joint health status of adult hemophilia patients. Methods Forty-nine adult hemophilia patients were selected. The quality of life and joint health status of patients were evaluated by hemophilia-specific health related quality of life questionnaire for adults (Hemo-QOL-A) and hemophilia joint health score (HJHS). Results The Hemo-QOL-A score of adult hemophilia patients was (39.34 ± 18.97) scores, and HJHS score was (33.16 ± 13.17) scores. The Pearson correlation analysis result showed that Hemo-QOL-A score was positively related with HJHS score (r = 0.490, P 0.05). In 294 joints of 49 patients, the total abnormal rate of the joint was 82.7% (243/294), the abnormal rate of the elbow joint was 72.4% (71/98), the abnormal rate of the knee joint was 90.8% (89/98), and the abnormal rate of ankle joint was 84.7% (83/98). Conclusions Decreased joint health status, mainly including the surrounding muscle condition and joint mobility, results in lower quality of life in patients with hemophilia. Key words: Hemophilia A; Hemophilia B; Quality of life; Joint health status