Correlation between preoperative factors and final visual acuity after successful rhegmatogenous retinal reattachment

Norifumi Hirata,Hiroko Terasaki,Eimei Ra,Takeshi Iwase,Misato Kobayashi,Kentaro Yamamoto

doi:10.1038/s41598-019-39839-2

Norifumi Hirata, Hiroko Terasaki + Show 4 more

Open Access

https://doi.org/10.1038/s41598-019-39839-2

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Journal: Scientific Reports	Publication Date: Mar 1, 2019
Citations: 13	License type: open-access

Affiliation: Nagoya University

Abstract

We evaluated the preoperative optical coherence tomographic (OCT) findings in eyes with macula-off rhegmatogenous retinal detachment (RRD) and determined the factors that were significantly correlated with the postoperative best-corrected visual acuity (BCVA). The length of the preoperative photoreceptors was defined as the distance between the external limiting membrane (ELM) and the outer end of the outer segments of the photoreceptors in the OCT images. The mean length of the photoreceptors was 102.8 ± 28.7 µm with a range of 20 to 159 µm in eyes with RRD. The length of the preoperative photoreceptors was not significantly correlated with the preoperative BCVA but it was significantly correlated with the postoperative BCVA (r = −0.353, P = 0.003). Multivariate regression analyses revealed that the length of the photoreceptors (β = −0.388, P = 0.001) and the preoperative BCVA (β = 0.274, P = 0.021) were the only independent factors that were significantly associated with the postoperative BCVA. The length of the preoperative photoreceptors was significantly correlated with the postoperative photoreceptor length (r = 0.486, P < 0.001). Longer preoperative photoreceptors were significantly correlated with longer postoperative photoreceptors and better BCVA after successful reattachment. These results suggest that the preoperative length of the photoreceptors can be good factor to use for predicting the final BCVA following successful reattachment of macula-off RRD.

Highlights

A rhegmatogenous retinal detachment (RRD) is a common cause of visual impairments, and a surgical reattachment of the retina is required for preserving vision[1]
Our results showed that the length of the preoperative photoreceptors was significantly correlated with the postoperative best-corrected visual acuity (BCVA) after successful reattachment of a macula-off RRD
The length was correlated with the postoperative outer retinal microstructures, viz., the photoreceptor length and the integrities of the foveal external limiting membrane (ELM), ellipsoid zone (EZ), and cone interdigitation zone (CIZ) microstructures

Summary

Introduction

A rhegmatogenous retinal detachment (RRD) is a common cause of visual impairments, and a surgical reattachment of the retina is required for preserving vision[1]. Optical coherence tomography (OCT) has been recently used to evaluate the retinal structure of eyes with a RRD in more detail These assessments include the detection of small cystoid cavities in the inner nuclear layer (INL) and/or outer nuclear layer (ONL)[12] and a dropout of photoreceptor back reflections[12,13,14]. Whether these structural changes are correlated with the postoperative visual acuity has not been determined[12,13,14,15,16]. There have been no reports on the association between the length of the preoperative photoreceptors and the postoperative BCVA and the integrity of the photoreceptor microstructures as determined by evaluations of the OCT images

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