Correlation between preoperative diagnosis and histopathological changes in preneoplastic cervical lesions

Abstract

The aim of our article was to study the concordance between the pre-operative and the postoperative histopathological diagnosis in 71 patients with preneoplastic cervical lesions. We included in our study 71 patients with preinvasive lesions of the cervix that were diagnosed and treated in our department. The preoperative diagnosis was based on cytology and colposcopy. Each case underwent a colposcopically guided biopsy and a histopathological examination of the biopsied sample. Five out of 71 patients showed high-grade squamous intraepithelial lesions, 48 patients showed low-grade squamous intraepithelial lesions and 18 patients, atypical squamous cells of undetermined significance changes. A good concordance was found between pre- and post-operative diagnosis. Our results highlight the necessity of a competent colposcopic diagnosis before the use of a therapeutic intervention in order to minimize misdiagnosis in preneoplasic cervical lesions.