Correlation Between Poison Severity Asessment And Outcome In Organophosphate Poisoning In Tertiary Care Hospital.

Abstract

To compare poison severity score with incidence of intermediate syndrome, ventilation and outcome in organophosphate poisoning. A retrospective study was conducted in a tertiary care teaching hospital of South India. Data was collected retrospectively from medical record section from 2012 to 2013 in a suitable designed case record form. Data was analysed by using SPSS 20.0 with chi-square and one way anova. Total of 199 cases of organophosphate poisoning was documented out of which 135 (67.8%) were males and 64 (32.2%) were females. The average age in this group of patients was found to be 34.22 + 14.26. The average pre-hospitalization period was 1.58 + 2.07 days. Among them majority of the cases were suicidal (94.5%). Patients with a poison severity score of grade 1,5. 8% had intermediate syndrome. In grade 2 only 33.3% had intermediate syndrome and the most was seen in grade 3 where 60% had intermediate syndrome. Patients with a poison severity score of grade 1 only 10.6% were on ventilation, in grade 2 only 56.7% were on ventilation and in grade 3,93.8% were on ventilation. Patients with a poison severity score of grade 1 had a recovery rate of 92.3%. Patients with a poison severity score of grade 2 had a recovery rate of 66.6% and patients with grade 3 had a recovery rate of 64.6%. As the severity in poison severity score increases other parameters like ventilation, intermediate syndrome and mortality also increases. There is a strong correlation between the poison severity score and outcome of the patient.