Abstract
Hydrogen peroxide, one of the main factors of Mycoplasma pneumoniae pathogenicity, is released in the reaction catalyzed by glycerol-3-phosphate (G3P) oxidase enzyme (EC 1.1.3.21). During the study, nucleotide substitutions in the glycerol-3-phosphate oxidase gene of Mycoplasma pneumoniae clinical isolates, the presence of which was accompanied by different levels of hydrogen peroxide production and cytotoxicity of Mycoplasma pneumoniae isolates regarding respiratory epithelial cells, were detected.
Published Version
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