Abstract
Organic extracts from airborne particles collected in 11 Italian towns between February and April, 1988, were tested for mutagenicity on TA98 and TA100 (± S9), and their nitroreductase (NR) deficient Salmonella strains, by the use of the Ames plate incorporation assay. Mutagenic responses were fitted by an equation which takes into account toxic effects on tester organisms. Generally parallel responses were obtained with the two Salmonella strains, but the TA98 gave, mostly, higher increases of revertants over the control level. No dramatic decreases in mutagenicity were observed with the NR derivative strains, except in a few cases with TA98NR and, more frequently, with TA100NR strains. During air sampling, temperature, atmospheric pressure, light, wind strength and direction, SO2, CO, NO2, O3 and non-methanic hydrocarbons (NMHC) concentrations were continuously monitored. Meteorological variables seem not to be significantly correlated with mutagenicity variations, while the highest correlation (r = 0.91) was observed between induced reversion in TA98 (+ S9) and NMHC concentration in air. Therefore, in spite of the wide range of different types of towns included in the study, air NMHC concentration can be considered a good predictor for the mutagenicity of the total organic material extracted from particles of urban air.
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