Abstract
Purpose: To evaluate the prognostic value of multifocal electroretinography (mfERG) after a decrease of retinal thickness in eyes with diabetic macular edema (DME). Methods: Sixty patients (60 eyes) underwent intravitreal injection of triamcinolone acetonide or bevacizumab for diabetic macular edema. Eyes were divided into three groups, according to foveal thickness : Group A (m, n=20 eyes), Group B (500 m≦m, n=20 eyes), and Group C (≧800 m, n=20 eyes). Best-corrected visual acuity (BCVA) and mfERG responses from the most central seven hexagons were analyzed both before and after treatment. Results: The pre-injection P1 amplitudes of mfERG correlated significantly with end-point BCVA in Groups A and B (p0.05) in Group C. Conclusions: The level of P1 amplitudes of mfERG may be a useful tool to predict visual outcomes after a decrease of retinal thickness in patients with diabetic macular edema.
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