Abstract
PCOS is a hormonal disorder common among women of reproductive age. Patients with PCOS are known to have a high incidence of insulin resistance. Serum magnesium (Mg) is often associated with insulin resistance among patients with PCOS. This case - control study was conducted at SRM Medical College Hospital and Research Centre, Tamil Nadu, India. Total of 62 participants between the age group of 20- 40 years were recruited in the study, in which 31 were healthy controls and 31 were cases with PCOS. FBG, HbA1c, lipid profile, serum magnesium, serum insulin was estimated. Students ‘t’ test was done to compare the mean levels between groups. Low serum magnesium, higher levels of insulin and insulin resistance is seen in PCOS compare to non-PCOS group. The correlation of analysed biochemical parameters were done among PCOS group. Negative correlation of mg with insulin, FBS and HOMA-IR was observed. The evidence showing that low serum magnesium is associated with insulin resistance in PCOS individuals.
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