CORRELATION BETWEEN LIPID PROFILE AND HbA1C IN GOOD AND POOR GLYCEMIC CONTROL TYPE 2 DIABETES MELLITUS PATIENTS AT A TERTIARY CARE HOSPITAL.

Abstract

Type 2 diabetes mellitus (T2DM) is a globally acknowledged health issue with its effect on human health, living standards, economy and health system. HbA C levels are routinely measured to monitor glycemic control. HbA C level 1 1 <7% is considered good glycemic control and HbA C level> 7% is considered poor glycemic control. Previous studies have reported that HbA C 1 1 level can be utilized as a possible biomarker for predicting dyslipidemia and consequent cardiovascular disease in diabetes mellitus patients. The aim of this study is to nd the association of lipid prole with HbA C in good glycemic control and poor glycemic control T2DM. This is a cross 1 sectional study conducted on 100 patients attending OPD with established diagnosis of T2DM of both sexes with no history of cardiovascular, renal or thyroid disease or history of lipid lowering drug intake. They were analysed for fasting (FBS) and postprandial (PBS) blood sugar, lipid prole and HbA C. Patients were classied into poor and good glycemic control groups based on their HbA C values. This study showed strong 1 1 positive correlation between FBS and HbA C. Lipid levels were higher in poor glycemic control groups with total cholesterol and low density 1 lipoprotein cholesterol showing signicant positive correlation with HbA C .Total triglycerides and HDL do not show any signicant correlation 1 with HbA C.