Abstract

Objective: To explore the consistency and relevance of the results of the bedside rapid blood gas analyzer GEM premier 3000, the Vitros5.1+5600 biochemical immunoassay analyzer and the SYSMEX XN-9000 automatic blood cell analyzer in the central laboratory detecting serum potassium (K+), serumsodium (Na+), blood glucose (Glu), hemoglobin (Hb) and red blood cell volume (Hct). And to provide a reference for the accurate interpretation of the bedside blood gas analysis report. Method: Usually, ICU patients will be taken arterial blood gas, biochemical and blood samples through the arterial indwelling needle; at the same time patients’ potassium, serum sodium, blood glucose, hemoglobin and red blood cell volume will be detected. This study implemented paired t-test and correlation regression analysis on each group of data, and used the analysis quality requirements (allowable total error) of CLIA’88 proficiency testing program as the criteria for clinical acceptance. Results: The paired t-test showed that the serum potassium, serum sodium and blood glucose detected by GEM premier 3000 and Vitros5.1+5600 were significantly different; and the hemoglobin and red blood cell volume detected by GEM premier 3000 and SYSMEX XN-9000 were significantly different (P +, Na+, Glu, Hb and Hct detected by the two sets of instruments is less than the allowable error of CLIA’88, and the SE of blood Na+ and Hb is less than half of the allowable error of CLIA’88. Conclusion: The test results of GEM premier 3000, the central laboratory Vitros5.1+5600 and SYSMEX XN-9000 have good correlation, but the consistency is not good. The test results of GEM premier 3000 cannot replace the central laboratory.

Highlights

  • The bedside rapid blood gas analyzer can get bleeding gas results in one minute, which makes it possible to realize rapid diagnosis and treatment for critically ill patients in the ICU, and brings convenience to patients and clinics

  • 1) Analysis of Differences A paired t test was conducted on two groups of data, and the results showed that the differences of the two groups of serum potassium, serum sodium, blood glucose, hemoglobin and red blood cell volume were statistically significant P < 0.05, see Table 1

  • The results showed that the two groups of serum potassium, serum sodium, blood sugar, hemoglobin and red blood cell volume are correlated P < 0.05

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Summary

Introduction

The bedside rapid blood gas analyzer can get bleeding gas results in one minute, which makes it possible to realize rapid diagnosis and treatment for critically ill patients in the ICU, and brings convenience to patients and clinics. Due to the differences in test methods and instruments, the results of testing the same items at the same time are different; besides there are differences between the rapid blood gas analyzer and the central laboratory [1,2,3]. This study intends to compare the differences and correlations of the results that 3 instruments (the clinical GEM premier 3000 blood gas analyzer, the central laboratory Vitros5.1+5600 biochemical immunoassay analyzer and the SYSMEX XN-9000 automatic blood cell analyzer) produce at the same time from detecting the same items in arterial specimens (potassium, serum sodium, blood glucose, hemoglobin, hemoglobin and red blood cell volume) and provide a reference for the accurate interpretation of the report of the bedside blood gas analyzer GEM premier 3000

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